Wednesday, October 30, 2019

Application Letter to the University of Fairleigh Dickinson Essay

Application Letter to the University of Fairleigh Dickinson - Essay Example I have always wanted to get a degree from a reputed university that will offer me innumerable opportunities in life from numerous perspectives. When considering applying to a university, I have based my choices and preferences on a number of criteria such as the reputation of the university, the cosmopolitan nature offered at the campus, the range of courses offered, importance to activities apart from study and lastly the emphasis laid on the exposure to internationalism. I strongly believe that among the choices that I have considered and researched, the Fairleigh Dickinson University certainly has come to outscore the others as it has provided me with such an insight that has left me mesmerized and created an urge in me to come in and experience the rich heritage personally. The first and the foremost things that captivated my thought when I had a look at the university web portal was the vast number of campuses, colleges and the range of mediums over which priceless education was being offered to prospective students. I sincerely felt that such an extended range of courses left me with much more than I could expect to choose from. I believe that it is extremely important in terms of my career to choose a course of my choice as I firmly believe that in order to succeed at work, true commitment and a liking for the job is a must. At a personal level, I have always wanted to support the expenses for my education and I was delighted and encouraged upon finding the extensive range of scholarship options that the university offers. I was also encouraged by the fact that the university plays host to a large contingent of students from other countries and I have always been willing to meet new people of different cultures and see the world through them. I strongly believe that if I get an opportunity to meet people from as much as 80 countries, my self-belief of being a global citizen will be further strengthened. I am also happy and encouraged by the

Sunday, October 27, 2019

Extraordinary Measures Film Analysis

Extraordinary Measures Film Analysis The film Extraordinary Measures is based on a true story which follows the journey of a father who is determined to save his young childrens lives. John and Aileen Crowley have three kids, two of which who have a rare genetic disorder called pompe disease. Pompe disease is a rare inherited disorder in which the glycogen in the body is not broken down, and thus the glycogen builds up within the bodys cells. This can cause muscular dystrophy and eventually lead to enlarged organs. The children born with this disease often times live a very short life of about ten years and die because their organs can no longer function with this glycogen build up. In the film, John Crowley has two children with pompe, but the story revolves around his eight-year-old daughter Megan. Megan just recently turned eight years old when she fell ill and was rushed to the hospital because to her respiratory system was starting to fail. While in the hospital, the doctor spoke to John and Aileen about Megans conditions. When explaining that her chances of survival were slim, he used the phrase think of it as a blessing when talking about Megans impending death. While the doctor was trying to help the Crowleys with this situation, the Crowleys obviously didnt want to think of their daughters passing away as a blessing. Though Megan survived, John didnt want to sit around and watch as his children were slowly dying in front of him, so he took matters into his own hands and reached out to Dr. Robert Stonehill. Dr. Stonehill was a scientist who was researching pompe disease and the enzyme that breaks down the glycogen in the body, which is missing in those d iagnosed with the disease. During their meeting, Dr. Stonehill explained to John that the university wasnt providing enough funding to allow him to further test his theory about the missing enzyme. When he told John that he needed at least half a million dollars, John and Aileen decided to create a pompe disease foundation to help raise the money to create the treatment. As John worked as an advertising executive, Dr. Stonehill saw that as an opportunity to work with John to create their own biotech company to research the enzyme. The only issue with this was they needed a lot more funding then the foundation was able to raise. Though John tried to get Dr. Stonehill to meet with investors, he was very uncooperative. Though the two of them often disagreed with one another, the one thing they agreed on was that it was important to find a treatment for the disease, thus allowing them to eventually come to terms and sign a business deal. Months into research on the enzyme, John realizes that the investors were unhappy with the slow progress of the study. Dr. Stonehill and John had promised that they would bring the enzyme into clinical trials in a year, but they werent making enough head way to do so. This lead to another disagreement between John and Dr. Stonehill, resulting in them selling their company to the competition. Dr. Stonehill, being the stubborn man he is, angered and annoyed many people in the company, leading to John going behind his back to make the competitors happy. A group of researchers, excluding Dr. Stonehill, went on to further enhance the enzyme. Eventually, the drug was approved to go into clinical trials, but the scientists agreed that they would use it on infants. As Johns children werent infants, they wouldnt be treated with the enzyme, which was John was working towards the whole time. This lead to John doing some unethical things, such as breaking into the lab and trying to steal the enz yme himself to give it to his children. Luckily, Dr. Stonehill was able to get John out of trouble, but there was still the issue that John worked for the company and using his children in clinical trials would be a conflict of interest. The movie concluded with John getting fired from his job, allowing them to use his two children in a sibling study. The film ended with his children laughing in their hospitals beds, showing what is called a sugar high, indicating that the enzyme was indeed working and breaking down the glycogen. In the beginning of the movie, it seemed to relate with the topic of the patient-professional relationship that was discussed in an earlier lecture in this course. When the Crowleys had a health scare with their daughter Megan, it seemed as if they didnt have a good relationship with the doctor. I understand that the doctor was trying to be professional and make sure not to give the family a false hope, but I believe that there could have been a different way to go about telling a family that their daughters chances of survival were slim. The doctor had used the phrase think of [Megans passing away] as a blessing. Personally, I feel as if using that phrase came off as a little insensitive. There is no easy way to tell parents that their childs chances of surviving were low. Also with the case of pompe disease, the family must need to visit various doctors all the time, so Im not sure if they have enough time to have a good relationship with the many doctors that they visit. Even so, when dealing with a disease as serious as pompe, I do believe that it would benefit the family to have a doctor that they trusted and had a good relationship with. Another topic that was discussed in this course was death and dying. When faced with death, many people often turn to religion as a way to cope. Though death was heavily touched in this film, religion was only mentioned once or twice. The part that stood out to me in the film regarding religion was when Megan was in the hospital when her respiratory system was starting to fail. John had mentioned later in the film that when she was on her death bed, he has prayed to God that if it was her time, that she would die fast and peacefully. While Megan herself did not pray, her father had turned to religion as a coping mechanism. When Megan did not die, John used this as inspiration and a sign from God that he needed to be the one to help save his daughter. This just shows one of the many ways that people can turn to religion to make themselves feel better. Personally, I think the thing about the movie that related most to this course is the ethics that are involved in this movie. It seems as a huge dilemma in this movie was between John and the scientists differing points of view. John was very passionate about finding a treatment for pompe disease because he was closely linked to the disease through his children who were affected by it. He was desperate to save his childrens lives. In the movie, it seem that his desperation got the best of him and he would have done anything to save his children such as stealing the enzyme from the lab. Though he didnt end up stealing the enzyme, he was willing to do anything to help his children. I know that if I was a parent, I would probably do anything myself to help my children live longer. Though the love he had for his children was strong, that still doesnt make what he was about to do right. When it came to the scientists, they were very conservative with what they did. They followed the rules very seriously. Dr. Stonehill on the other hand did not. He was also willing to do anything to help these children. When John brought in the families who were affected by pompe disease, one of the scientists was upset. He explained to John that science was not a field that should get mixed up in emotions. If the scientist got emotional, they were willing to do anything to save those childrens lives, even changing the results to show that the drug worked. While I do agree that its important the scientist is truthful about the results, I also believe that being emotionally connected to a project could benefit the scientist in a way. I see nothing wrong with a scientist being motivated by their emotions to work on a project, as long as the scientist is truthful in their results. They need to remember that their job is to help people, and if they skip steps or lie about results, that c ould ultimately hurt more people in the long run. The film Extraordinary Measures touched many of the topics that were mentioned in this course thus far. It showed examples on how it is very important to have a medical team that you have a good relationship with and trust. In hard times, such as having a close call with losing a child, I believe that it is extremely important to have a good support system. In that support system, I think that its also important to be able to have a doctor that you trust fully. You want to know that your child or loved one is not only in the hands of someone that knows what they are doing, but someone who cares about them as a patient.ÂÂ   It showed that many families, if not the patients themselves, turn to religion as a coping mechanism during hard times. I believe that it is very therapeutic to turn to religion as a coping mechanism in hard times. Like in Johns case, he used religion as an inspiration and push into looking for a cure for his children. Personally, I am a firm believer that eve rything happens for a reason. This way of thinking can be hard if something terrible happens, but in the end I do think it helps with looking at the silver lining. The film also showed that it may be hard to be passionate about something but also to follow the rules and not let your emotions get in the way of the purpose of the study. Passion is a very good motivator for many things and people. It can help you get through the days that you feel you are too tired to do something. It can help you push through the bad days when it feels as nothing is going your way. Its a fantastic motivator if you use it the correct way. You need to make sure that your passion doesnt cloud your judgement and get in the way of ethical solutions. Overall, I think the movie showed the importance of teamwork in the medical field. While it is important to be passionate about what you do, it is also important to be reasonable. John and Dr. Stonehill showed passion in different ways. John showed passion in finding a cure as his childrens lives were depending on the cure and he was running out of time with them. Dr. Stonehill showed passion in his research and finding a treatment to help those who had the disease. The scientists in the movie were the more responsible, logical characters. The scientists, while wanting to find a treatment, also knew the importance of following policy. They didnt want to pursue a study if there were not going to be any results. They knew the FDA regulations, and wanted to make sure that they were followed. As much as they wanted to help find a treatment, they wanted to make sure they were not overly optimistic and there was a successful outcome in the end. This movie is a direct indicator that humanit ies are important in not only the medical field, but any science field, and as long as people work together and combine their knowledge and the humanities, they can make a difference in the medical field.

Friday, October 25, 2019

Faustian Deal in The Woman in White, The Picture of Dorian Gray, and D

The Faustian deal and subsequent fall is a common theme throughout literature, and with each new iteration sheds increased light on the character of the individual and of society. The Woman in White by Wilkie Collins, The Picture of Dorian Gray by Oscar Wilde, and Dr. Jekyll and Mr. Hyde by Robert Louis Stevenson are all texts which exhibit the Faustian deal and descent, complete with Doctor Faustus and Mephistopheles counterparts. Sir Percival Glyde, Dorian Gray, and Dr. Edward Hyde are all characters who are ultimately lead to their moral downfalls by their respective Mephistopheles counterparts. Specifically, the characters of Sir Percival Glyde, Dorian Gray, and Dr. Henry Jekyll fulfill and contrast the Faustian archetype, who are aided in their moral descent by their Mephistopheles foils, Count Fosco, Lord Henry Wotton, and Mr. Edward Hyde respectively. The characters of the different novels will be compared against one another and a discourse about what their varying motivation s reveal about their respective moral compasses will be conducted. Among other vices the characters exhibit, vanity plays a prime part in their individual development. Vanity is a detriment on the individual, and serves as a driving force behind the three character’s motivations, ultimately leading to their respective downfalls. At its core, the Faustian deal is a contract between an individual who aspires to be or achieve a type of greatness and a devil who enables the individual to do so at a severe cost. There are different versions, including the original German legend, Johann Wolfgang von Goethe’s Faust and Christopher Marlowe’s The Tragical History of the Life and Death of Doctor Faustus. Most typically, as in the case of the titular Faust of leg... ...pr. 2014. Marlowe, Christopher. Doctor Faustus. Ed. Sylvan Barnet. 2nd ed. New York: Signet Classics, 2010. Print. Puhvel, Martin. "Mephostophilis's Manipulation of Faustus." English Studies 71.1 (1990): 1-5. Literary Reference Center. Web. 02 May 2014. Sanyal, Arundhati. "Taboo in The Picture of Dorian Gray." The Taboo. Ed. Harold Bloom and Blake Hobby. New York: Bloom's Literary Criticism, 2010. 147-56. Print. Stevenson, Robert Louis. Strange Case of Dr Jekyll and Mr Hyde. New Lanark: Waverley, 2008. Print. Wilde, Oscar. The Picture of Dorian Gray. Ed. Joseph Bristow. Oxford: Oxford UP, 2008. Print. Yirinec, Jennifer A. "Re-Envisioning the Faust Legend: Christopher Marlowe's The Tragical History of Doctor Faustus and Richard Burton and Nevill Coghill's Doctor Faustus" Literature Film Quarterly 41.1 (2013): 67-76. Literary Reference Center. Web. 03 May 2014.

Thursday, October 24, 2019

Favorite Genre Essay

There are many different genres of movies – science fiction, romance, drama, adventure, comedy, to name a few. Certain ones appeal more to some people than others. In my opinion, adventure, comedy, and science fiction are the best of all the genres. Adventure movies top the list when it comes to being the best. They are full of action, have good story lines, and keep me on the edge of my seat. Adventure movies are thrilling and never boring. What I like best is finding it easy to imagine myself as part of the adventure. Some of my favorite adventure movies include â€Å"Lord of the Rings†, â€Å"Chronicles of Narnia†, â€Å"Pirates of the Caribbean†, and â€Å"National Treasure†. There are more adventure movies in the list of the best top 10 movies from 2004-2006 than any other type of movie. The second most popular type of movie over the past three years has been comedy movies. I too agree that comedy movies are wonderful. Everybody likes to laugh, including me. It is said that laughter is the best medicine. With all the bad things going on in the world today, everyone needs to have a good laugh every now and then. Some of my favorite comedy movies include â€Å"Shrek† and â€Å"Shrek 2†. The third most popular type of movie at the box office is science fiction. This is also my third favorite type of movie. Science fiction movies are thrilling, suspenseful, and action filled. They can be scary too. Science fiction movies are typically â€Å"guy movies†. They allow for limitless imagination. Some of my favorite science fiction movies include all the â€Å"Star Wars† movies, â€Å"Alien vs. Predator†, â€Å"Men in Black†, and â€Å"War of the Worlds†. So, in my opinion, adventure ranks number one, comedy ranks number two, and science fiction ranks number three. According to the results at the box office, I’m not the only one who thinks so. So, go to the movies or rent an adventure, a comedy, or a science fiction movie and enjoy!

Wednesday, October 23, 2019

Development of police -Time line history Essay

The Roman Vigiles are recognized world over as the first police force. Gaius Octavius who was Julius Caesars’ grandnephew created this â€Å"non-military and non-mercenary police† in 27 B.C. (Berg, B.1998) The creation of the force followed the assassination of Julius Caesar and Gaius sought to reform the Roman society as a form of revenge. This was done once Gaius ascended to power to become Augustus Caesar the â€Å"first emperor of Rome.† (Berg, B.1998) However it was not until the 17th century that elements of policing started being practiced in the US after being adopted from the English watch system. This system was to later evolve to the American watch system, which had a form of silent, and unseen policing based on â€Å"hue and cry.† (Berg, B.1998) Among the first parts to adopt this system was the Boston night watch formed in 1631; this system enlisted 6 watchmen, a constable and many volunteers. American policing is normally classified into 3 distinct eras that are discussed below. The political Era (1840-1930) The major characteristic of this era was the close relationship between the police on one hand and politicians on the other. This relationship in most cases was geared towards â€Å"making the politician happy† The police system was very decentralized and its main purpose was to provide basic social services. Inherent in the police system during this era was the endemic corruption. http://www.realpolice.net/police-history.shtml   Sometimes this era is called the â€Å"Spoils Era† which called for large-scale adaptation to the social changes that were taking place in America. This era is named so because as the term puts it â€Å"to the Victor go the spoils† whereby the political class in big cities often controlled their municipal police. http://www.realpolice.net/police-history.shtml During the period of 1835 America was hit by numerous Industrial and race riots, which involved mostly the Native Americans and the immigrant Irish. In response to these riots, the police force was assigned the function of controlling them. However, because the type of system used was variably inadequate and ineffective the answer was found in police officers that would be salaried. (Walker, S.1998) 1845 marked the beginning of a salaried police force in America. This was in New York City where the police were called â€Å"coppers† because of the copper star badges they wore. They worked throughout, day and night mainly to control riots. http://www.realpolice.net/police-history.shtml The â€Å"coppers† were armed with guns and were usually trained to think smarter than their working class counter parts. This system was to soon spread to other states like Boston where detectives and informants were being used and Philadelphia with the characteristic â€Å"mug shots.† http://www.realpolice.net/police-history.shtml The Texas Ranger which was founded in 1845 is mentioned as the first state police organization and it is always well remembered for the atrocities against Mexicans and â€Å"Comanche tribes.† However, the Pennsylvania Constabulary is generally accepted as the first professional state police agency. The constabulary initial functions was to aide mine-owners against strikes in the mines. (Walker, S. 1998) The California Gold Rush of 1848 prompted the formation of Federal police agencies that included the Border Patrol, the IRS, Postal Inspector and the Secret Service. In1855 Allan Pinkerton was a model for federal investigators after founding the Pinkerton’s private security agency. Other agencies that sprouted up during this time were Holmes Burglar Alarm Company and the Brinks and Wells Fargo armored delivery services. By early 20th century the Spoils era was coming to a close, ending in 1900 when the Pendleton Act came into being. This Act was mainly enforced by a civil service system to fight corruption and nepotism. Several innovations were made, and the form of policing shifted from â€Å"brawn to brain†. (Berg, B.1998) During this time professionalism took center stage and led to the formation in 1902 of the International Association of Chiefs of police (IACP). Richard Sylvester became the body’s first president; he was also the Washington D.C.P.D chief and is widely recognized as the â€Å"father of police professionalism.† Many aspects of paramilitary policing were developed during this time. (Walker, Samuel 1977) By 1918, August Vollmer as the chief of the Berkeley P.D became   â€Å"the patriarch of police professionalism†. During his time, for the first time in America advancement in crime labs and finger printing were realized, more and bigger police stations were built accompanied by change of job titles. The professionalism saw the establishment of police unions at the bottom ranks. (Walker, Samuel 1977) In 1915, the Fraternal Order of Police (FOP) was established. The establishment of the Federation Of State County Municipal Employees (AFSCME), and the International Conference Of Police Association (ICPA), the umbrella group of teamsters, followed this. Another aspect of this era was the involvement of citizen groups in the police reforms a notable model was the Chicago Crime Commission. The commission was more of civilian oversights board that sort to bring intellectual ideas about causes of crime. During this era policewomen were given the chance to do real police work, for the first time. Another peculiar development during this era was the Volstead Act on the 18th Amendment or Prohibition in 1919.This was an era characterized by gangsterism of such renowned gangsters like Al Capone and John Dilinger. It was also a time during the Great Depression where there was widespread unemployment and law was unenforceable. Thus the main function of the police during this time was fighting crime because the number of gangsters had increased and they had become more organized. It was this period that is often described as the Prohibition Era when attempts were made to ban alcohol sales and consumption. (Walker, S. 1998) All together there was an escalation of such crimes as kidnapping, daylight bank robberies and drive by shooting. The police were under intense pressure to contain the runaway crime and most time resorted to the use of brute force including the use of dirty tricks. Notable police leaders who emerged during this time were J.Edgar Hoover and Elliot Ness. They often used covert means and latest technology to check on the raising crime. The advent of the two ways radio, the police car and the telephone transformed greatly the policing system to become a more reactive system. (Gaines, L.& Vaughn J. 1999) The Reform Era (1830-1980)   The reform era was ushered in by various transformations that started taking place in the police system in the 1920s led by August Vollmer who was Berkeley, California Police Chief (Carte, G. & E. 1975). During this era new technology started being adopted and greater professionalism enhanced (Walker, Samuel 1977). Such professionalism centralized the command and control of the police operations. Such officers like O.W Wilson who introduced professionalism in Wichita, Kansas and the Chicago police drastically reduced corruption. Here training of the police was greatly emphasized. (Bopp, W 1977) O.W. Wilson introduced various strategies like rotation of officers from one community to another to reduce corruption incidences, strict merit promotion system, and higher salaries to attract professionals and aggressive recruiting drives. (Bopp, W 1977) However, there remained a bad relationship between the police on one hand and the minority communities on the other because of the highly autocratic police leaders. The police during this period despite of the reformations concentrated more on felonies and other serious crimes. (Bopp, W 1977) The 1960s were marked by urban unrests that included movements such as the civil rights, the Vietnam, the student rights and counterculture. There was an escalation of serial and mass murders with an increased number of police killed in the line of duty that averaged 100 annually. The crime rates soared tripling during this period. (Carte, G. & E. 1975). In 1968 the National Advisory Commission on civil disorders blamed the riots on the police and following the abolishment of the death penalty 1967-1977,the police were faced with a heavy task of checking on the rise in crime whilst doing it professionally. In 1965 President Johnson formed the Presidents Commission On Law Enforcement And Administration Of Justice whose reports were influential in providing an overhaul criminal justice system model. It was during this period that the police information system became computerized and more emphasis was placed on empowering the criminal justice system. (Carte, G. & E. 1975). In the 1970s the interest shifted to the Police Community Relations when the reactive policing approach was found to be ineffective. Corruption in the police force was still endemic and various commissions were formed to investigate it. Such commissions were common and were formed by citizens and financed by the private sector or community groups. (Walker, S. 1998) Various programs were started towards enforcing the police community relations and included such programs as open houses and ride a longs, citizen self defense trainings, citizen police academies and â€Å"Coffee Klatches† or community meetings. These outreaches helped the police realize their public safety function, where â€Å"fighting the fear of crime was as important as fighting crime itself† (Gaines, L.& Vaughn J. 1999) The Community Era (1980- Preset) Many law enforcement agencies in the 1990s started adopting strategies of community policing and problem oriented policing. Problem oriented policing that was characterized by a centralized problem pinpointing approach came first. (Gaines, L.& Vaughn J. 1999)   Community policing defined as â€Å"a philosophy based on citizens and police working together in creative ways to help solve contemporary problems related to crime fear disorder and decay†. (Gaines, L.& Vaughn J. 1999) Community policing is characterized by the incorporation of the public in combating crime, where the police are more involved with the community they police, now than ever before. (Gaines, L.& Vaughn J. 1999) It was also during the 1990s that New York Police Department developed an information based crime pattern tracking and mapping system. The system’s purpose was to check the trends and patterns in crime and the accountability of dealing with crime problems is given to the police.

Tuesday, October 22, 2019

The protective role of glutathione Essays

The protective role of glutathione Essays The protective role of glutathione Essay The protective role of glutathione Essay Glutathione is the most abundant intracellular non- protein thiol and has been implemented in many cellular functions including detoxification of xenobiotics, cell cycle regulation, regulation of gene expression, protection of macromolecules and as an anti-oxidant.  Glutathione synthesis is a two step process catalysed respectively by ?-glutamylcysteine synthase and glutathione synthase.  Step 1) L-glutamate + L-cysteine + ATP( L-Y-glutamyl- L-cysteine + ADP + Pi . Step 2) L-Y-glutamyl L-cysteine + glycine + ATP ( GSH + ADP +Pi  Glutathione appears to be synthesised primarily in the cytosol, yet serves its function in other compartments including the nucleus, mitochondrial matrix, endoplasmic reticulum and in the extracellular environment. There appear to be two intracellular glutathione pools, one accounts for between 70 and 85 percent, is located in the cytosol and exhibits a rapid turnover with a half -life of between 30 minutes and 2 hours. A less significant pool resides within the mitochondria having a longer half-life of around 30 hours. Glutathione breakdown is catalysed by a specific enzyme, glutamyltransferase located on the luminal plasma membrane of epithelial cells.  Protective functions of glutathione.  The role of glutathione in xenobiotic metabolism.  The metabolism or biotransformation of foreign compounds can be divided into two phases. Phase one, the modification of a compound, achieved by the addition of a functional group such as a hydroxyl group and phase two, the conjugation of the functional group to convert the compound into a more polar and hence more readily excreted form.  Glutathione conjugation is probably the most important phase two reaction, being a major detoxification pathway for many compounds with a chemically reactive centre. Such substrates include aromatic rings, double bonds, halogenated aromatics, aliphatics and acyclics. Conjugation of various epoxides with glutathione.  The dimeric enzymes catalysing these transformations are glutathione-S-transferases and exist in four major classes;  An example of glutathione conjugation is in the metabolism of large doses of paracetamol, (acetaminophen), a widely used analgesic and anti-pyretic drug. Paracetamol is relatively safe when taken at therapeutic doses, however it is becoming increasingly common for overdoses of the drug to be taken for suicidal intent. Paracetamol poisoning causes primary centrilobar hepatic necrosis and possible renal damage and failure. The metabolism of therapeutic doses of the drug is generally via glucoromidation, but for doses in excess of aound 10 tablets, glutathione conjugation becomes significant. One product of paracetamol oxidation via cytochrome P450 is N-acetyl-p-benzoquinoneimine (NAPQI). This electrophile is detoxified in the liver via conjugation with glutathione, alternatively, it is reduced back to its parent compound also by the action of glutathione. In the case of an overdose, reduced glutathione can become saturated and as a consequence, when the levels drop to around 20 percent of normal, NAPQI has a tendency to react with other molecules within the cell possessing sulphydril groups. This leads to the oxidation of these cellular proteins, particularly enzymes, for example the plasma Ca2+ATPase. The inhibition of this calcium pump leads to the increased storage of calcium by the endoplasmic reticulum and by the mitochondria, however, these two stores have a finite capacity and if saturated, the intracellular concentration of calcium can become extremely high, resulting in cellular damage. It has been observed in rats fasted overnight and then administered with a paracetamol overdose, that as glutathione levels drop to around 20 percent, lipid peroxidation can occur. In conclusion, glutathione appears to be very important in paracetamol toxicity, in fact reduced glutathione is administered clinically in cases of paracetamol overdose and if given in time can limit the potential damage caused in such cases.  Detoxification of H2O2 and other organic peroxides.  Oxygen, although critical for aerobic life, is potentially toxic. Dioxygen (O2) itself is a free radical, but is relatively stable owing to the position of its free electrons- occupying parallel spin positions. However, the reduction or partial reduction of oxygen can generate damaging free radicals, their unpaired electrons conveying high chemical reactivity on the molecule, such as the superoxide anion. All aerobic cells generate these free radicals as a consequence of oxidative metabolism. Glutathione can protect against oxidative damage in the cell in two ways, both directly and indirectly.  Free radicals, owing to their high chemical reactivity, attack a wide range of macromolecules. Often, this results in chain reactions whereby the product of one reaction serves to propagate further reactions. One means of terminating this process is by one free radical attacking another. However, free radicals are relatively rare in biological systems, therefore, various protection mechanisms have evolved. One such mechanism is that of free radical traps and glutathione itself serves as a free radical trap. Being small and water-soluble it works in the aqueous phase of the cell, reacting with free radicals to yield glutathione radicals and a reduced form of the free radical. In contrast to many free radicals, the glutathione radical is stable, un-reactive and does not go on to propagate further reactions.  Glutathione can partake in the protection against free radicals indirectly via the action of glutathione peroxidase. Glutathione peroxidase is an enzyme abundant in areas of high oxidative stress. It was discovered in 1957 by Mills and is unusual in possessing a selenium co-factor, which works as illustrated.

Monday, October 21, 2019

Double Indemnity essays

Double Indemnity essays In Double Indemnity Phyliss and Walter are planning the murder of Phyliss husband. But greed and lust dont always bring out the love. In this essay I will pull out each mise en scene out of each scene to capture the true evil intentions of Phyliss, and show how she is truly a daemon. In this first meeting we are at Phylisss house. Her house is very large and cost about $30,000 according to Walter the insurance agent. We meet Phyliss here for the very first time in the movie. Her maid answers the door when Walter comes to the house to talk about the insurance policy. After answering the door we see Phyliss in the balcony almost naked, wearing only a white towel around her body and talking very seductively to Walter. After the brief talk with Walter in the foyer she walks towards her room? Well whatever she walks towards is not light up, it is all black which may really suggest that she is wearing a white towel but really she is black inside. Walter comes into her living room and waits for Phyliss to come down after she gets changed. Room lighting is just daylight coming in through the blinds nothing great. Phyliss comes into the room wearing an all white dress. She sits down on her sofa with a shadow covering one side of her face; really Phyliss is not a good woman. As the two engage in there conversation Phyliss gets up and walks around the room, as she is doing this she happens to walk in front of the fireplace a few times her dark shadow is casted on to the white backing of the fireplace and fallows her like a daemon. As we come to the end of this scene we can all see that they both want each other. The next scene here we come back to Phyliss house. Walter has come back to talk to her husband about the insurance policy. Phyliss is wearing a white shirt with black flowers on it, a black dress, and also black shoes, her clothing shows her true intentions starting to come out. Phyli ...

Sunday, October 20, 2019

How to Become a Forester - Career Path

How to Become a Forester - Career Path This is the second in a three part series on becoming a forester. As I mentioned in the first feature, there is a structured set of courses you must have from an accredited forestry school to become a forester. However, when you finish your four year degree, the practical applied learning process begins. Working conditions vary considerably - you may be inside for weeks at a time. But it is a certainty that a large part of your job will be outside. This is especially true during your first several years of employment where you are building career basics. These basics become your future war stories. Although some of the work is solitary, most foresters have to also deal regularly with landowners, loggers, forestry technicians and aides, farmers, ranchers, government officials, special interest groups, and the public in general. Some work regular hours in offices or labs but this is usually the experienced forester or forester with a graduate level degree. The average dirt forester splits his/her time between field work and office work, many opting to spend most of the time outside. The work can be physically demanding. Foresters who work outdoors do so in all kinds of weather, sometimes in isolated areas. Some foresters may need to walk long distances through thick vegetation, through wetlands, and over mountains to carry out their work. Foresters also may work long hours fighting fires and have been known to climb fire towers several times a day. Foresters manage forested lands for a variety of purposes. Generally they come in four groups: The Industrial Forester Those working in private industry may procure timber from private landowners. To do this, foresters contact local forest owners and gain permission to take inventory of the type, amount, and location of all standing timber on the property, a process known as timber cruising. Foresters then appraise the timbers worth, negotiate the purchase of timber, and draw up a contract for procurement. Next, they subcontract with loggers or pulpwood cutters for tree removal, aid in road layout, and maintain close contact with the subcontractors workers and the landowner to ensure that the work meets the landowners requirements, as well as Federal, State, and local environmental specifications. Industrial foresters also manage company lands. The Consulting Forester Forestry consultants often act as agents for the forest owner, performing many of the above duties and negotiating timber sales with industrial procurement foresters. The consultant supervises planting and growing of new trees. They choose and prepare the site, using controlled burning, bulldozers, or herbicides to clear weeds, brush, and logging debris. They advise on the type, number, and placement of trees to be planted. Foresters then monitor the seedlings to ensure healthy growth and to determine the best time for harvesting. If they detect signs of disease or harmful insects, they decide on the best course of treatment to prevent contamination or infestation of healthy trees. The Government Forester Foresters who work for State and Federal governments manage public forests and parks and also work with private landowners to protect and manage forest land outside of the public domain. The Federal government hires most of their foresters for managing public lands. Many State governments hire foresters to assist timber owners in making initial management decisions while also providing manpower for timber protection. Government foresters also can specialize in urban forestry, resource analysis, GIS, and forest recreation. Tools of the Trade Foresters use many specialized tools to perform their jobs: Clinometers measure the heights, diameter tapes measure the diameter, and increment borers and bark gauges measure the growth of trees so that timber volumes can be computed and future growth estimated. Photogrammetry and remote sensing (aerial photographs and other imagery taken from airplanes and satellites) often are used for mapping large forest areas and for detecting widespread trends of forest and land use. Computers are used extensively, both in the office and in the field, for the storage, retrieval, and analysis of information required to manage the forest land and its resources.Thanks to BLS Handbook for Forestry for much of the information provided in this feature.

Saturday, October 19, 2019

International relations major Personal Statement

International relations major - Personal Statement Example Saudi Arabia ranks among the fastest developing countries, which experience high rates of migration to different parts of the world. In addition, the country’s relationship with other nations is at its peak due to various factors such as the terror war, oil trade, politics, and sports. The issue of Islam and terrorism, as well as the position of women in the Saudi Arabian public, is essential motivators to study International Relations. These aspects of the society have motivated me to study the subjects in order to understand the influence of reaction, interactions and actions of governments’ policies on humanity. I firmly accept that an influential and so far-reaching subject warrants a critical understanding and analysis at higher levels. My elementary and high school education prepares me adequately to study International Relations. I received broad education in various subjects such as mathematics, literature, and history as well as politics. The extensive knowledge in many subjects enables me to communicate effectively with individuals from different parts worldwide during the course of the degree. Additionally, my singing ability enables me to disseminate information regarding various political and economic issues in Arab. The motivation to sing triggers me to explore current political, economic and social events across the world. My main educational goal is to attain a doctorate in International Relations in order to establish a stable career in the field. The motivation to enroll for the International Relations courses results from the knowledge I have acquired through extensive reading of different political materials since childhood. In addition, my dad bought political books, and historical books play a significant role in my interests in the subject. I also engaged my father in extensive discussion of the current issues in various countries such as international politics and crisis in gulf and Palestine. I anticipate

Friday, October 18, 2019

Public Administration Policy AnalysisAnalytical paper that will Research

Public Administration Policy AnalysisAnalytical that will analyze and make a recommendation on a policy issueNATIONAL POPULATION CONTROL - Research Paper Example Increase in the population generally has a very great impact on the country. It leads to various other problems in education and employment. People do not get an opportunity to select the educational institution that they prefer. This subsequently affects their employment. Employment has become a big issue since the numbers of educated people are more when compared to other countries. The U.S nationals are deprived of their chances due to the increase in the immigration. Population control is the major concern of any country. The governments of almost all the countries around the world try their best to control the population though there are various population control techniques; the lack of co-operation leaves the policies ineffective. Population control cannot be achieved overnight and the government and other public service organizations must implement unique population control mechanism. (Mosher, 2008).The importance of population control has been realized over the past few years and almost all the countries struggle hard to control the population. United States is one among the countries which has taken up this issue seriously. Due to the various external factors, the American government has proposed new ideas that can control the population. The current population in U.S is more than 30 crores and there... (Haub, 2008). The current population in U.S is more than 30 crores and there has been an increase in the fertility rate when compared to the past. When compared to the 20th century the population in U.S has tripled and the census has revealed the fact that U.S population cannot be controlled instantaneously. (Dexter, 2009). There are various issues that have contributed to the increase in the population. The immigration, increase in the fertility rate and the lack of sex education are the major reasons for the increase in the population. The various issues with their respective alternatives are discussed below. Immigration Immigration is one of the main reasons for the increase in the U.S population. There has been an enormous increase in the number of people who emigrate from other parts of the world. The development in the science and technology has grabbed the attention of many and people prefer U.S when compared to the other states. U.S has been one among the best places for the students to pursue their higher education. These people who pursue their education gradually settle down in U.S as soon as they get a suitable job. This in turn adds to the population and this also has a disadvantage. The natives of U.S are deprived of their chances in education and employment. (Haines, 2000). A survey that was conducted by the U.S Census Bureau reveals that the number of immigrants in the year 2005 was around 1.4milliion. This research also shows that the number of people who immigrate to U.S in the year 2050 will be around 2.1 million per year. This clearly states that the immigrants play a major part in the U.S population and the decrease in the number of immigrants will prove to be a relief.

Negotiation Essay Example | Topics and Well Written Essays - 1500 words

Negotiation - Essay Example Additionally, the discussion would incorporate revealing the most essential lessons that can be learned from the Stitt Feld Handy negotiation simulations and designing an effective negotiation skill for future implementation. Integrated Discussion Prior Understanding and Experience of Negotiation According to my perception and practical experience, negotiation is often observed as an effectual tool especially when there lay any sort of conflict or disagreement amid the parties regarding any issue or event. It can often be termed as a significant aspect which may act in different ways such as in a descriptive, narrative or in a prescriptive manner (Babcock & Lascheve, 2008). In general, the basic negotiation approach can be characterized into various types such as structural, strategic, behavioral, concession exchange and integrative negotiation approach (Food and Agricultural Organization of the United Nations, 2008). With regard to my personal experience, the primary objectives of a ny negotiation process generally comprise substance goals as well as relationship goals. In relation to the substance goals, the outcomes are generally identified in accordance with solving various issues or complexities. It is worth to mention that the prime intention of an effective negotiation process significantly involves three major attributes such as quality, harmony as well as efficiency that enable both the parties to supportively act with each other to mutually accomplish their respective interests. Therefore, my feeling towards the concept of negotiation is that the process is nothing but a decisive tool which can be implemented to address different sorts of conflicts or disputes that takes place amid the parties (McCuddy, n.d.). In accordance with my own experience, I had participated in negotiating few numbers of conflicts wherein the parties possesses dissimilar preferences and interests. In this regard, one of my experiences which dealt with resolving the conflict bet ween the managers and the team members of a particular organization can be taken into concern. The conflict mainly emerged due to the happening of an accident in the production unit resulting in a labor to be physically harmed. In response, the management of the organization charged a certain amount of money to the labor because of the damage to certain valuable production related materials or components. This eventually raised the conflict between the labors and the management team of the organization by a greater degree. In this scenario, I have been witnessed to visualize an effective form of negotiation process wherein the managers and the team members of the organization are mutually agreed upon to adopt a beneficial decision. The decision has been made through balancing the interests of both the parties. My response towards this particular negotiation was to identify the actual cause which led to the conduct of such unforeseen accident. In this regard, I pointed out that the i neffective training provided by the management to its laborers ultimately caused the accident. Therefore, the negotiation procedure aimed at mutually mitigating the raised conflict between the management and the laborers through compromising their respective

Why Do So Many Teenagers Run Away From Home Research Paper

Why Do So Many Teenagers Run Away From Home - Research Paper Example Mother's death or a stepfather's sexual molestation, increased divorce rate, lack of care and attention from the parents etc are some of the other major reasons for the teenage run away from home. Teenage runaway from home results in many social problems. The teenagers who take shelter in the streets often engage in antisocial activities like, robbery, violence etc. Moreover, these teenagers often face sexual exploitation and antisocial elements make use of such teenagers for conducting their missions. This paper briefly analyses the causes and effects of teenage run away from home. Why Do So Many Teenagers Run Away From Home? â€Å"Typically, a runaway is defined as a person under the age of eighteen voluntarily leaves home or another residence and thereby the custody of parents or guardians† (Flowers, 2001, p.3). Even though run away has no uniform definition, we can generally define it as leaving of home by the teenagers without their parent’s permission. Runaways ar e classified into four categories; floaters, runaways, splitters; hard rock freaks Floaters leave home for a shorter period whereas the runaways usually result in long periods of isolation from home. Splitters are the ones who leave their home for pleasure seeking whereas hard rock freaks leave their home permanently having chosen a life of their own (Flowers, 2001, p.4). Earlier, the relationships between the parent and the children were so strong and hence the runaway problems were less. Parent-children relationship has been changed a lot in the current century. It was a divine relationship earlier and became diplomatic at present. The generation gap is growing between the parents and the children. The parental rights now have been transformed as parental responsibilities. Right and responsibility have huge differences. The terms right have much more significance than responsibility. Today’s parents consider their commitments towards their children just like a responsibilit y rather than their right. The transformation of parental responsibility from right to a responsibility has decreased the relationships between the children and parent and subsequently runaway problems started to increase. The parents fail to identify the teenage problems correctly. They have their own personal, professional and social problems and hence failed to spend more time with their children in order to identify their needs. In short, lack of parental care is one of the major reasons of teenage runaways. A relatively high incidence of runaway behaviour may be indicative of family discord. Adolescent runaways believe that their homes were conflictual and intolerable (Rohr, 1997, p.4). Family problem is another major reason for the teenage runaways. The conflicts between the parents often create problems to the development of children. Drug addiction or alcohol addiction of either of the parents may create family problems. In America single parenthood is growing because of the increased divorce rate. A teenager needs the care and attention of both the father and mother and in the absence such love and care, he/she may think in terms of running away from home. In a divorced family the children were forced to stay with either hi/her father or mother, which may result in getting only the half attention he deserves. Mother plays a crucial role in her child’s life. Mothers play the most part in raising the kids. Her role can be three quarters of parenting. Nevertheless, the role they play prior the birth. Nobody can substitute her. She bonded with her kids from the early days of pregnancy to a very late age. She teaches her kids the norms and right behaviours. Father's role is complement to mother's role and yet very important. Father is the person whom the child

Thursday, October 17, 2019

PetMeds annotated outline Case Study Example | Topics and Well Written Essays - 500 words

PetMeds annotated outline - Case Study Example The products are also advertised on the internet platform through social media and video advertisements (PetMeds Express, Inc, 2012). Emails are used to persuade new customers. Old customers are reminded to make purchases through the emails, as well (PetMeds Express, Inc, 2012). The website of the company is also an effective means of marketing the products. The products sold by the company are purchased directly from four major manufacturers. However, these manufacturers offer a variety of resources that cater for the needs of all customers (PetMeds Express, Inc, 2012). Customers make orders directly from the company’s website (PetMeds Website). Optionally, a customer can make a toll-free call to the company’s customer representatives to place an order (PetMeds Express, Inc, 2012). The company has a program in which customer care representatives receive training, on a continuous basis, from training officers. These representatives take care of customer complaints and compliments hence evaluation of customer satisfaction is possible (PetMeds Express, Inc, 2012). After making the order, the company’s supply-chain section, based Pompano Beach, processes the order and ships it to customers across the US. Customers can track the progress of their orders through the company website (PetMeds Express, Inc, 2012). This section analyses the market threats of the company and how it has achieved to counter them. The company has experienced stiff competition from veterinarians and other retailers, traditional and online based. In fact, the veterinarians have even engaged in a litigation battle with the company (Fiala, 2012). However, the company commands a greater market share due to the affordability of its products, promptness in delivery and convenience. The company’s net profits have been relatively flat in the past years, and this is attributed to the increased administrative and general expenses. Nevertheless, this is set to improve in the

'China should prioritise improving its relationship with the ASEAN Essay

'China should prioritise improving its relationship with the ASEAN countries over its relationship with the US'. Discuss - Essay Example It is indeed, an open secret that the relationship between some countries is more cordial, integrative and coordinated than others. Commonly, a nation will consider a number of factors before deciding the type of countries it would forge alliance or relations with. Over the past decade or two, the need for economic advancement and growth has become one of the most paramount factors considered in the stake for selecting partner (Hyer, 2004). Political factors have also been very influential as a means of seeking political dominance. Like all other countries, China has its own international partners and coordinated countries. China’s relations with the United States for instance have been one of the most talked about over the past decade. Apart from the United States, China also has had a higher level of relationship with the Association of South Eastern Asian Nations (ASEAN). In this essay, there is a careful scrutiny to the relationship that exists between China and the United States as well as China and ASEAN to discuss why prioritizing her relationship with ASEAN would do more good to China than a prioritized relationship with the United States. Overview of International Relations International relation is basically the study of relationship that exists between countries. ... ernational relations is a pathway that leads to and brings about an essential and itemized formulation of foreign policy strategy (Dowdy and Trood, 2007). What this means is that countries engage in relationships with other countries as a means of forging and achieving long term foreign policy plans to rule their nations. Commonly, countries want to achieve political and economic power over others. But to make political dominance possible, the counties ought to have several representation and seats in as many international organizations and institutions as possible (Prakash, 1994). To this end, they would relate with other countries so as to gain voting support when the need arises for such international office elections. For economic dominance to be possible also, it is important that countries have as many international markets as possible as the size of a country’s market is proportional to the size of its economy (Shenon, 2005). Against this backdrop also, countries would want to have as many international partners as possible. Indeed, as long as the phenomenon of the League of Nations through the United Nations Organization continues to exists, there is the tendency that such flexibility and allowances that make easier inter-national relations will continue. History of China-US relations The relationship between China and the United States dates back to 1844 when it took place in the form of the Treaty of Wanghia in 1844. Among other factors, the treaty and for that matter relationship was necessitated as a means as allowing much and easier accessibility of the movement of people and good to and from the two countries. To this end, there was the fixing of trade tariffs for the two countries. Citizens of the United States were also allowed the freedom or right to

Wednesday, October 16, 2019

PetMeds annotated outline Case Study Example | Topics and Well Written Essays - 500 words

PetMeds annotated outline - Case Study Example The products are also advertised on the internet platform through social media and video advertisements (PetMeds Express, Inc, 2012). Emails are used to persuade new customers. Old customers are reminded to make purchases through the emails, as well (PetMeds Express, Inc, 2012). The website of the company is also an effective means of marketing the products. The products sold by the company are purchased directly from four major manufacturers. However, these manufacturers offer a variety of resources that cater for the needs of all customers (PetMeds Express, Inc, 2012). Customers make orders directly from the company’s website (PetMeds Website). Optionally, a customer can make a toll-free call to the company’s customer representatives to place an order (PetMeds Express, Inc, 2012). The company has a program in which customer care representatives receive training, on a continuous basis, from training officers. These representatives take care of customer complaints and compliments hence evaluation of customer satisfaction is possible (PetMeds Express, Inc, 2012). After making the order, the company’s supply-chain section, based Pompano Beach, processes the order and ships it to customers across the US. Customers can track the progress of their orders through the company website (PetMeds Express, Inc, 2012). This section analyses the market threats of the company and how it has achieved to counter them. The company has experienced stiff competition from veterinarians and other retailers, traditional and online based. In fact, the veterinarians have even engaged in a litigation battle with the company (Fiala, 2012). However, the company commands a greater market share due to the affordability of its products, promptness in delivery and convenience. The company’s net profits have been relatively flat in the past years, and this is attributed to the increased administrative and general expenses. Nevertheless, this is set to improve in the

Tuesday, October 15, 2019

Health Project management Essay Example | Topics and Well Written Essays - 750 words

Health Project management - Essay Example After the determination of the main agenda, preliminary steps prior to implementation are undertaken such as the gathering of the tools and resources required in every aspect of administration and implementation of the objectives. After this, the planning phase required prior to implementation is needed. In the said phase the specific schedule of the actions are indicated (Dwyer, Stanton and Thiessen, 2004). The culmination of the said phases is the implementation phase where the skills of the personnel, the leadership of the head and the teamwork and cooperation of the different units and members are crucial to the success of the project and the attainment of the goals and missions. The said factors are very crucial in the implementation of the health project since governance can make or break the goals of the project. If any of the said factors fail, the whole system is affected. Facing project scope creep can be considered as a common phenomenon in the process of project implementation. This is a common case based on the fact that the plans are made and implemented by human being. Scope creep is defined as the ‘low-key’ incremental changes upon project implementation (Melton and Iles-Smith, 2009, p.118). There are different issues related to scope creep such as requirements creep, feature creep and instruction creep. Requirements creep can be related to the changes in the scope of requirements due to the changes or variation in the disposition of the end user. In a health project, it can be related to the procedures required for a particular case, patient or project. The feature creep on the other hand is related to the unforeseen features that can arise in the development of the project. These issues are often originating from the people implementing the project on the basis of the view to improve services. This is important to uphold the quality

Monday, October 14, 2019

Beliefs of Calvin and Augustine

Beliefs of Calvin and Augustine The Traditional Calvinist view to the doctrine of Perseverance of the saints finds its origin in the philosophy of the sixteenth-century Swiss Reformer John Calvin (1509-1564). He wrote and published the first edition of his Institutes of the Christian Religion. This is the most about writing on systematic theology which the world had ever known at that time. To this present day his belief have pervade spread through the Protestant world. Because God is sovereign over all His creation, Calvin argued, He must be the sole actor in the salvation of His human creatures. He believed that any response, prior to regeneration, from a depraved human being would make God less than sovereign in human redemption. John Calvin drifted from his Roman Catholic faith while studying the vast writings of Augustine, the Roman Catholic Bishop of Hippo (354-430). He constantly praised Augustines work with frequent quotes and references from his writings. Many prominent Calvinists acknowledge that Calvins fundamental beliefs were through the writings of Augustine and were already formed while he was still a faithful Roman Catholic. He systemized Augustines doctrines, which have been developed, for the most part, the Five Points of Calvinism presented today. Augustines influence remained with him throughout his life. The beliefs of Calvin and Augustine embody the Five Points of Calvinism presented today. Just as the Synod of Dort, (the synod which first formally presented these points as the Five Points of Calvinism-TULIP),[1] was a Calvinistic Synod, so John Calvin was an Augustinian. These Augustinian teachings that he presented in his Institutes of the Christian Religion included the sovereignty of God, which made Him the cause of everything, including sin, election, and the predestination of the elect to salvation and of the non-elect to damnation. Professor Herman Hanko, co-authored one of several books called TheFivePointsofCalvinism,written to explain and defend Calvinism, says that: Boettner agrees. He says: Calvinist theologian R. Laird Harris states that: We see that John Calvin took what Augustine had written and refined it. Many of our doctrines that we understand and recognize today have developed from earlier stages of belief. This is the case with the doctrines of Augustine. An example of this is the doctrine of Eternal Security. He did not teach this, but he was a crucial figure in establishing the root source that is the basis in which this doctrine could develop in to how we understand it today. With a little research, one can understand how his influence on theology as a whole goes without question. The foundational beliefs, biases, and doctrines that many believers have today, Protestants and Catholics, are to be discovered in the beliefs of Augustine. While most Calvinist and Catholic theologians agree with Augustine, some Protestants do not. However, most of them, if not all, will acknowledge his huge influence on Christian beliefs and doctrines. Augustine was born November 13, 354 in Tagaste Numidia. He was brought up in a divided household: Augustines father was not a Christian and directed his son towards secular knowledge which could bring him an income. When he became an adult, Augustine moved to Carthage and he took an interest in debating. Around the year 375, Augustine became a Manichaean Gnostic. Augustine was a Manichaean for nine years and was greatly influenced by them, whose doctrines were heretical. The Gnostics believed in two gods, one evil and one good. Some Gnostic groups renounced marriage and procreation. Many believed that the dualism of flesh and spirit-the flesh being evil and the spirit being good. Many historians have noted that Augustine has brought this Manichaean influences into the Church. The Manichaean teachings are believed to have influenced Augustines doctrine of the total depravity of mankind, the elect and predestination. These are the foundations and essential elements of the doctrine of Eternal Security that was to follow after Calvin got a hold of them. Because of Augustines sinful lifestyle, he could not advance in the Manichaean religion. He had a reputation of being a fornicator and a womanizer. Historian James ODonnell, is a University Professor at Georgetown University. He says: Later Augustine became a skeptic and turned to the philosophy of Neo-Platonism (a form of thought rooted in the philosophy of Plato). He began to merger these beliefs with his Gnostic and Christian beliefs. Augustines writings were strongly influenced by his studies in Neo-Platonism, Gnosticism, and the Christian Scriptures. Much like Calvinists today, he used Scripture out of context to match his theology. In 384, Augustine went to Milan as a incredulous professor of rhetoric. Before he left Milan in 388, he had been baptized by Ambrose and was indebted to Ambroses Catholic Neo-Platonism, which provided a philosophical base that eventually transformed Christian theology.[2] Augustine was not only influenced by the Manichaean Gnostics, but he was also being influenced by his mentor Ambrose. Ambrose had absorbed the most up-to-date Greek learning, Christian and pagan alike-notably the works of Philo, Origen, and Basil of Caesarea and of the pagan Neo-Platonist Plotinus.[3] With his philosopher ideas mixing Scriptures with Platonism with its elements of mysticism and some Judaic and Greco-Roman reading, he influenced Augustine in his theology. Maybe this is why, that no one that has ever lived has influenced Christian theology as Augustine has. He is responsible for much of what we consider to be Catholic doctrine today. Not surprisingly, he is also credited with being a major participant in Protestant beliefs as well. The historian Jaroslav Pelikan remarked: Commenting on Augustines book entitled, The City of God, the historian Edward Gibbon wrote: [1] A century after the Reformation a reaction against this extreme Genevan Calvinism developed around Amsterdam pastor and theologian, Jacob Arminius. After his untimely death in 1609, some of his followers, the Remonstrants, pressed his denial of Calvinism in five points. At the Synod of Dort (1618-19) they were banished from the Netherlands Reformed churches by the Calvinists, who set out their doctrine in five opposing points, the famous acronym, TULIP. [2] Encyclopà ¦dia Britannica, Inc., Saint Ambrose, (Last accessed 7/31/15): http://www.britannica.com/EBchecked/topic/19014/Saint-Ambrose [3] Encyclopà ¦dia Britannica, Inc., Saint Ambrose, (Last accessed 7/31/15): http://www.britannica.com/EBchecked/topic/19014/Saint-Ambrose

Sunday, October 13, 2019

The Personification of Death in Jean Cocteau’s Orpheus Essay -- Movie

The Personification of Death in Jean Cocteau’s Orpheus The personification of Death is done by means of a princess of the Underworld in Jean Cocteau’s Orpheus. This Princess is very powerful, yet surprisingly vulnerable. For no one is allowed to love in the Underworld, the Princess falls in love with a famous poet named Orpheus and goes to drastic measures to be with him. But in the end she cannot be with her love, and she realizes this and does what is forbidden in the Underworld and defies time and sends back her love to whom he loved before her. Death in Cocteau’s Orpheus is not only powerful and vulnerable, but she also changes throughout the course of the movie. Three elements support that the Princess changes throughout the course of the film and what brings about this change. These elements are dialogue, clothing and appearance, and actions. One way that Cocteau creates the Princess’ character by the usage of dialogue. The powerful Princess Death is a very harsh, and controlling character at the beginning of the movie. She is seen as very authoritarian and demanding. The first scene in which the viewer encounters the princess, she orders Cegeste, Heurtebise, and Orpheus. This is the first time that the princess is ever seen by Orpheus and the first words that she speaks to him are very harsh and demanding. The Princess is accompanied by a young poet named Cegeste, and when Cegeste is killed by the motorcyclists she orders Orpheus to help her and to come as a witness. She then continues her orders by ordering the chauffer, Heurtebise, to not go to the hospital, but to go â€Å"the usual route†. She continues in her harsh tone of voice by ordering the motorcyclists. Every person that the Princess converses with in the begin... ...s also seen when she can kill people with a single glance and then raise them to be her servant in the Underworld. She chooses to raise Cegeste to be her personal slave. Her vulnerability is displayed when she watches Orpheus sleep. Despite the Princess’ power, she becomes vulnerable and defies the rules of the Underworld and return’s Orpheus back to life. This action proves that the Princess has a true love for Orpheus and does not worry about the consequences of doing what her heart feels right. Cocteau suggests that there is a higher power than even Death itself. The Princess personifies Death, but she is controlled by the Committee of the Underworld. If she were the most powerful facet of Death, then she would not be controlled by anyone or anything. Therefore, the Princess in Jean Cocteau’s Orpheus represents not Death, but one of the many faces of Death.

Saturday, October 12, 2019

Hamlet Essay -- Shakespeare

‘Critics often judge Gertrude as a weak, selfish and innocent woman, caught up in conflicts she does not fully understand.’ To what extent do you agree with this? The two female characters in Shakespeare’s tragedy seem to be drowned in the mist of the deceitful power-game played by the male characters, which contribute to the on-going tragic conventions of murder, revenge and betrayal so prevalent in this form of drama. The title of Hamlet’s metatheatrical play-within-a-play, 'the mouse-trap' is as applicable to the plot of Shakespeare’s 'Hamlet'; set in the especially patriarchal society of Elsinore, which is dominated by the authoritative actions of the male characters, Hamlet may be seen as a tragedy where the female characters have small and seemingly unimportant roles in the tragic plot compared to the climactic ‘masculine’ moments – the visitations of the Ghost, the dramatic agon between Hamlet and Claudius and the final conquest between Hamlet and his counterpart Laertes. Gertrude is a character whose fate is tragically overshadowed by the power of these men, indicative of the submissive role o f women in the Jacobean period. Despite the fact that directors often present Gertrude as a sensual and deceitful woman who is vain and self-satisfied with strong sexual appetites, if one looks to Shakespeare’s text, this character has a very small and arguably innocent voice in the play; indeed Rebecca Smith argues that ‘Gertrude’s words and action create not the lusty, lustful, lascivious Gertrude that one generally sees in stage and film productions but a compliant, loving, unimaginative woman whose only concern is pleasing others’. In order to assess Shakespeare’s characterisation of the Queen, it is necessary to exami... ...arded as selfish, weak and innocent, caught up in a conflict that she more than understands. Works Cited Bamber, L.(1990) â€Å"Class Struggle: Shakespeare and Sexism.† The Women’s Review of Books 7:5. Bradley, A.C. (1966) Shakespearean Tragedy. New York: St. Martin's Press. Burnett, Mark, ed. (1994) New Essays on Hamlet. New York: AMS Press. Granville-Barker, Henry. (1970) Prefaces to Shakespeare. New York: Hill and Wang. Heilbrun, Carolyn. (1957) Hamlet’s Mother. California: University of California Press. Kolin, Philip C. (1991). Shakespeare and Feminist Criticism an Annotated Bibliography and Commentary. New York: Garland. Loske, Olaf. (1960) Outrageous Fortune. Oslo: Oslo University Press. Shakespeare, William. Hamlet. Shakespeare, William. Macbeth. Smith, Rebecca. ‘A Heart Cleft in Twain: the Dilemma of Shakespeare’s Gertrude’.

Friday, October 11, 2019

Rh Bill Case Study Essay

There are 6 bills pertaining to reproductive health and/or population management that have been filed for deliberation in both the House of Representatives and the Senate for the 15th Congress. The most controversial of these bills is House Bill No. 96 authored by Rep. Edcel Lagman. House Bill No. 96, also known as the proposed â€Å"Reproductive Health and Population and Development Act of 2010,† will cover the following areas: * midwives of skilled attendance * emergency obstetric care * access to family planning * maternal death review * family planning supplies as essential medicines * benefits for serious and life-threatening reproductive health conditions * mobile health care service * mandatory age-appropriate reproductive health and sexuality education * responsibility of local family planning office and certificate of compliance * capability building of barangay health workers * ideal family size * employers’ responsibilities * multi-media campaign * implementing mechanisms * reporting requirements * prohibited acts * penalties The bill is controversial, as it is being opposed by concerned citizens, especially the pro-life, pro-family and pro-God groups, regardless of creed or religion. The Roman Catholic Church expresses its opposition against the bill on many counts, most especially the procurement and distribution of family planning supplies for the whole country, when the available evidence from peer reviewed medical journals supports the hypothesis that when ovulation and fertilization occur in women taking oral contraceptives (OCs) or using intrauterine devices (IUD), post-fertilization effects are operative on occasion to prevent clinically recognized pregnancy. Hormonal contraceptives and/or IUDs directly affect the endometrium. These effects have been presumed to render the endometrium relatively inhospitable to implantation or to the maintenance of the preembryo or embryo prior to clinically recognized pregnancy. These make pills and IUDS abortifacient. Pro-life groups, and many professionals in the medical and nursing fields, believe that physicians and policy makers should understand and respect the beliefs of patients who consider human life to be present and valuable from the moment of fertilization. Patients should be made fully aware of this information so that they can consent to or refuse the use of artificial contraceptives. However, the position of the Catholic Church and the pro-life groups does not mean that they espouse the attitude of â€Å"natalism† at all costs, as if the â€Å"number† of children, in itself, were the unmistakable sign of authentic christian matrimonial life. The sexual act, properly exercised within marriage only, is ordained primarily to the propagation of life. If there are reasonable motives for spacing births, such as serious medical conditions in the mother, or extreme poverty, then the Catholic Church teaches that married couples may take advantage of the natural cycles of the reproductive system and use their marriage precisely those times that are infertile (natural family planning). Other aspects of the bill being contested by concerned citizens include the classification of family planning supplies as essential medicines when their safety/toxicity profile and legal permissibility are questionable. At the same time, more importance should be given to the prevalent diseases, the top ten leading causes of morbidity and mortality in the Philippines, namely, infections such as pneumonia and tuberculosis. Financial resources allotted by foreign donors to assist the Philippine government programs could actually be better spent towards pursuing health programs targeting communicable diseases than purchasing artificial contraceptives. Very pertinent to the debate about reproduction rights is the right to life. The Philippine Constitution says that the State â€Å"shall equally protect the life of the mother and the life of the unborn from conception. If artificial contraceptives are medically proven to induce abortion as one of their mechanisms of action, then procurement and distribution of such family planning supplies are unconstitutional and illegal. INTRODUCTION The international aid environment has undergone considerable change in recent years. Internationally, principles of development cooperation. In some countries, civil society has achieved success in navigating the aid architecture and advocating effectively on behalf of sexual and reproductive health (SRH). In other countries, interacting and participating in key development processes has been more challenging due tolack of sufficient data or evidence to make a strong advocacy case, and weak understanding of terminology and processes, making access and influence difficult. For the past two years, WHO has supported the AHEAD project (completed in January 2011) implemented through the German Foundation for World Population (DSW). DSW had provided financial and technical support to civil society organisations (CSO) for developing and implementing locally devised advocacy action plans to raise levels of government funding for SRH in three countries. The countries are Bangladesh, the Philippines and Uganda. This report is a case study from the AHEAD project in Philippines. The case study begins by describing the socio political context in which the AHEAD project was implemented. The context covers three themes – an account of civil society movements, situation analysis of sexual and reproductive health and rights and background to the policy environment in the Philippines. The subsequent sections highlight findings from evaluation of the project including achievements from the implementation of the advocacy action plan, the challenges faced by AHEAD and finally the lessons learned. Literature Review The Reproductive Health Bill (RH Bill) has drawn opposing opinions from different sectors of the society. There are people who propose and support the RH Bill and there are those who strongly oppose it. Some find themselves in a crossroads wherein they agree on certain components of the RH Bill but remain doubtful about the other parts. Moral, economic and political conflicts continue to rise between opposing sectors. The debate goes on and on. The primary goal of the RH Bill is to guarantee universal access to methods and information on birth control and maternal care. There are six bills sharing common goals. There seems to be a general agreement when it comes to maternal and child health care but conflicts have risen concerning the proposal that the private sector and Filipino taxpayers fund the nationwide distribution of family planning devices to help control the country’s population. Meanwhile, the government shall continue giving out information on their uses through he alth care centers. Issues and arguments †¢ Population The Philippines has the fastest growing population in Southeast Asia. Studies have shown that most pregnancies in the Philippines, especially among the poor, are unplanned. Supporters of the RH bill claim that the increasing population of the country is something that cannot be ignored anymore. RH bill principal author Edcel Lagman said, â€Å"The Philippine population is growing at a much faster rate than can be sustained by the government or the country’s resources.†Lagman said that the Philippines is the only country in Southeast Asia that does not have a national reproductive health bill. Based on studies made by the University of the Philippines (one example here), the country tops the fertility rate in Southeast Asia at 3.3 percent. Following are Malaysia at 2.5 percent and Vietnam at 2.1 percent.

Thursday, October 10, 2019

Microeconomics and the Law of Supply and Demand Essay

During the simulation of Goodlife Inc. I was able to see how the effects of a lower rent verses a higher rent had on the vacancy percentage. In our simulation the town of Atlantis had only one rental agency with apartments available. There were single family homes available too but the need for renting was with apartments. I got to see how the supply and demand worked with this rental property simulation. The town of Atlantis saw a rise in population which led to a higher demand for vacant units. This caused Goodlife to raise its rent to meet the growing demand for its available units. But as the demand for renting the units fell so did the demand. This meant Goodlife had to lower its rental price to meet the lesser demand for renting. This is a good example of microeconomics. When I looked at the simulation for examples of macroeconomics I found it when the government stepped in to put a cap on the rent amount. In the simulation there was a survey that showed individuals were living outside of Atlantis rather than renting a place in the city limits where they work. As many of us do currently in our own lives we usually can’t afford to live in the city or area where the best jobs are. I am a prime example, I commute 50 miles one way to work as it’s where the best salary is. I live in an area where housing and rents are affordable and the overall cost of living is cheaper too. In the simulation, the government put a cap of $1550 for the monthly rent of a two bedroom apartment. This was meant to allow middle class families and individuals the opportunity to live where they work. Because of the rent cap, Goodlife didn’t rent out every apartment available as profits would not be able to keep up with the maintenance cost of having every uni t rented. When we look at what a shift in supply and demand curve we see that clearly when Lintech Inc. moved into Atlantis creating more jobs. As soon as  Lintech did this it increased the population of Atlantis which was the shift in the supply curve. This was a negative impact for Goodlife as there was more population needing apartments and not enough two bedroom apartments available. The demand curve now goes up because of the population growth and need for more apartments. With Lintech moving into the city and the population now increasing the demand it means that the quantity demand is now more than quantity supplied at the original equilibrium. This also caused a temporary shortage in the market of two bedrooms apartments in Atlantis. Rental rates went up due to the higher demand. Also quantity demand decreased and quantity supplied increases which leads to a reduction of apartments or shortage of apartments. To get to the new equilibrium the adjustment needs to get between the new demand curve and the original supply curve. When the new equilibrium is reached the rental rates are now higher than they were before. This also means that the number of apartments that are demanded and the supply of apartments has also increased. I can apply this supply and demand to my workplace job. When I have a customer that wants to ship more packages with us on a new daily bases I have to look at the new demand. Before their demand for shipping more I didn’t need extra couriers and trucks to handle the day’s deliveries. Now with the new demand I have to get my supply of couriers and trucks at the last minute. This causes me to have to spend more money to rent more vans and hire more employees. Overall my cost go up with the demand of more shipping packages, but so does my profit as I am able to use more supplies to handle the new demand. To better understand how the concept of microeconomics helps me understand the factors that affect shifts in supply and demand on the equilibrium price and quantity I have to look at the competitors and their prices. The bidding for the competition and where it comes across the equilibrium is the point at which the new equilibrium is now. But under the view of macroeconomics it is seen when the jobs and population grew. This effected the increase and decrease on the available apartments. Now the equilibrium  for rentals is higher then it was before the move in by Lintech. So is the number of apartments demanded and supplies has increased. In the simulation we saw how with lower prices meant that the demand was higher. But with the demand for apartments came higher prices. But if the price was to increase too much the demand for apartments would decrease. There is also a possibility that it could remain the same over a short period of time, then decrease if prices didn’t change. This simulation showed lots of possibilities that could exists in today’s world, or at least in Atlantis. We see what price could do to supply and demand for apartments and what demand could do to price and supply. When either is moved or switched leads to various outcomes the will lead an economy like Atlantis to either run out of its supply of apartments or have an increase in supply of apartments because the prices are too high. Reference Microeconomics, Ninth Edition, David C. Colander (2013) University of Phoenix

Wednesday, October 9, 2019

A Simulation Of Sustainability In Urban Environments Environmental Sciences Essay

In 1987 the World Commission on Environment and Development, ( WCED 1987 ) stated that â€Å" Humanity has the ability to do development sustainable to guarantee that it meets the demands of the present without compromising the ability of future coevalss to run into their ain demands † . There Out of the many definitions of sustainability this profound statement has become the most widely accepted. It is what these demands are, how we impact upon them and how out impact can be measured or assessed that raises the most argument. ( Parkin et al. 2003 ) Sustainability is frequently symbolised utilizing three over lapping circles ( fig 1 ) , stand foring the three facets of sustainability ( society, economic system and environment ) . However this simple diagram over simplifies the complex interactions which occur between the facets and the big figure of indexs which are used to mensurate our impact. Unless these complex interactions are clearly understood by all the stakeholders it would be impossible to to the full measure the sustainability of any development ( Foxon et al. 2002 ) . A figure of determination support tools have been created to help determination shapers in accomplishing sustainable urban developments. There has been immense attempt and resources put into making DSTs, yet despite this most are seldom used due to either the complexness of their operation or the complexness of their end product ( Isaacs et al. 2007 ) . It is hence believed that there is a demand for new determination support tools that can cover with the complexness of urban design and which go beyond the proficient orientation of old tools ( Sahota & A ; Jeffery 2005 ) to enable a robust appraisal of sustainability within the decision-making procedures. Visual image has been used to help determination devising in a figure of Fieldss including increasing the safety and effectivity of oil boring in the oil and gas industry ( Evans et al. 2002 ) , visualizing medical informations ( Fuchs et al. 1989 ) and battlefield simulations ( Hix et al. 1999 ) . Geographic Information systems are presently the most extensively used visual image platform for determination devising. â€Å" GIS is now a standard point in contrivers ‘ tool kits † ( Drummond & A ; Gallic 2008 ) and there are many illustrations its usage in urban planning and determination devising over the last 20 old ages ( Harris & A ; Elmes 1993 ; Stevens et Al. 2007 ; States 2000 ; Shiffer 1998 ; Lodha & A ; Verma 2000 ) . Traditionally GIS provides the user with a synergistic information researching interface which allows them to cover a figure of different maps onto a 2D surface and allows the user to carry on complex geospatial analysis ( Salter et al. 2009 ) . Howe ver it has been shown ( Lowe 2004 ; Lowe 2003 ) that many non-expert stakeholders have great trouble in decoding and understanding scientific shows and maps. Due to its complexness and high acquisition curve GIS requires the user â€Å" to believe like a geographic information scientist † ( Clarke 2001 ) and is still considered to be a hard to utilize, adept tool ( Traynor & A ; Williams 1995 ) . Its usage in determination devising has made it hard for non expert stakeholders, particularly the general populace, to take part to the full in be aftering determinations ( Salter et al. 2009 ; Al-Kodmany 2002 ) . Most GIS systems are purely 2D, covering with geospatial informations being draped over a map or other geographical representation. While experts can imagine the ocular impact of a proposed development from this program view it is really hard for person non trained in the usage of GIS to make this. This can take to non-expert stakeholder non to the full understanding the effects of the determinations being made and go forth them with an unintended positive or negative position of the planned development ( Danahy et al. 1999 ) . 3D representations nevertheless allow users to rapidly recognize the spacial context of the determination and besides to orientate their position of the proposed development ( Danahy et al. 1999 ) . Peoples develop the ability to voyage and visually process 3D representations of urban environments on a bomber witting degree throughout their lives as they walk through existent universe metropoliss ( Charters et al. 2002 ) . This sub witting ability means that t he user will non hold to work to visualize the development but can concentrate on the determination, and the effects of the determination, being made. SCITY VT S-City VT ( sustainable metropolis visual image tool ) is a paradigm determination support application that is designed to let a wider scope of stakeholders input into the sustainability planning procedure by leting the stakeholders to compare different scenarios utilizing a usage designed simulation and visual image engine. Figure 1: Visual image techniques used in S-City VT The visual image engine utilises a split screen rendering attack which allows the user, utilizing any of the techniques, to compare two scenarios side by side throughout the life rhythm of the development. A figure of visual image techniques have been used to expose the consequences of the implicit in simulation engine which allows the user to non merely compare the external visual aspect of the different scenarios but besides the comparative sustainability of each scenario. As already discussed traditional GIS does non supply a realistic physical representation of the metropolis or development being studied. CAD system do enable the creative activity of 3D theoretical accounts which provide the user with a realistic representation of the edifices and the developments ( Al-Kodmany 2002 ) , nevertheless CAD systems provide no ability to cover extra informations and supply small context out with the edifice or country being studied. The visual image engine combines GIS and 3D urban theoretical accounts and embeds the 3D theoretical accounts in the environing landscape to contextualise the urban country that is undergoing sustainability appraisal. The ability to visualize portion of the metropolis that is undergoing the development or regeneration within the wider metropolis context is likely to better battle with the communicating tool and convey a greater degree of engagement from all participants in the planning procedure ( Levy 1995 ) Fig 4: 3D representation of proposed development within the city-wide context. The usage engine allows the user to hold synergistic control enabling the user to see the proposed development from any imaginable point of view. This allows the user to go to the full immersed in the proposed development, to a much greater grade than 2D programs, GIS, or rendered 3D stills. As has already been shown ( Isaacs et al. 2010a ) S City VT provides the user with a feasible representation of the existent development. Design to Virtual RealityBlendingFig 5: Overview of the index blending technique The blending technique, as shown in figure 5, merely takes the all the sustainability steps for each index, calculated by the bomber system and ANP theoretical accounts, unite them into a individual value. This valued is so mapped to a individual coloring material graduated table. The coloring material graduated table used can be selected from a figure of color graduated tables known for their discriminating abilities ( Levkowitz & A ; Herman 1992 ) these include the het object, magenta, local optimised, and spectral. Using the hot-cold graduated table demonstrated in figure 5 a edifice or floor with high comparative sustainability would look blue while a edifice with low sustainability would look ruddy. This method gives a individual index of sustainability and provides the easiest manner of comparing the comparative sustainability of different options or scenarios.WeavingFig 6: Overview of the index weaving technique Whilst the blending technique, combines the index values, the weaving technique ( figure 6 ) efforts to continue some of the implicit in information so that the user can still place which indexs or bunch are doing the greatest consequence ( negative or positive ) on the sustainability of the edifice. The coloring material weaving technique ( Hagh-Shenas et al. 2007 ) uses a different coloring material graduated table for each index ( figure 6 ) to try to continue this information. The colors from each graduated table are so indiscriminately weaved into a hodgepodge like texture which is applied to each floor of the edifice. The size of the squares or spots in the weave can besides be changed depending on the user ‘s penchants. A little spot size will give an overall representation of the sustainability, with darker sunglassess stand foring low sustainability and lighter sunglassess stand foring higher sustainability. A larger spot size will let user to place rapidly which colou rs stand out the most, and hence which indexs are holding the greatest impact.Traditional Graphical TechniquesRadar graphs, figure 7, let the stakeholder to compare the sustainability of different edifices based on the index values. The form, size, coloring material and point values will be different for each edifice leting a elaborate comparing. Fig7: Comparision of scenarios utilizing traditional radio detection and ranging graphs and coloring material weaving. Parallel coordinates allow the user to compare all index values for all the edifices in a scenario ( fihure 8 ) . Buildings can be selected and their hint in the graph is highlighted. The colors in the graph correspond to those in the blending technique. Fig 8: Parallel co-ordinate graph for sample development. Simple temporal graphs secret plan the all the index values over the life clip of the development. These allow the user to place the interconnectivity of the indexs and to place where and why sudden alterations occur ( figure 9 ) . Fig 9: Index graph demoing alterations in 6 indexs over clip.Real Time SimulationThe index patterning involves developing bomber theoretical accounts that define how each of the indexs vary over infinite and clip. The S-City VT application is built utilizing a modular model supplying flexibleness and leting index theoretical accounts to be changed. For the paradigm application six sustainability index theoretical accounts ( credence, lodging proviso, energy efficiency, noise pollution, employment and economic benefit ) have been developed four of which are described below:Energy EfficiencyThe energy efficiency theoretical account is based on the Nation Calculation Method ( NCM ) which is the industry criterion leting energy efficiency of edifices to be determined ( BRE 2009 ) . The NCM method takes into history a broad scope of factors, including figure of room accesss, Windowss glazing type, exterior building, figure of floors etc, to bring forth a metric depicting the energy effici ency the edifice. A NCM study was developed utilizing the NCM tool, stand foring the typical edifices in the development for a figure of different options including external visual aspect and different mixes of edifice usage. Fig2: Graph demoing temporal alterations in sustainability index due monthly energy fluctuations. This information is input to the energy efficiency theoretical account and attenuated with the temporal energy ingestion informations ( BIS 2009 ) which reflects how the energy usage of the edifices change depending on the clip of twelvemonth. ( fig 2 ) shows how the sustainability index alterations as a map of clip for a 2 different constructing types with different utilizations ( glass, commercial and brick, residential ) .Noise PollutionThe noise theoretical account calculates the degrees of traffic noise geting at each edifice and can besides cipher the proportion of people that will happen certain degrees of noise a nuisance. Datas about the jutting traffic flows for the waterfront development were sourced from Dundee metropolis councils Dundee Waterfront Traffic & A ; Signing Report ( White Young Green 2007 ) . For each route in the proposed development a noise degree is calculated utilizing its projected hourly traffic flow. Using a map provided in CRT ( 1988 ) , ( equation 1 ) this traffic flow can be transformed into a noise degree which corresponds to how loud, in dBs ( dubnium ( A ) ) , the traffic noise is if the hearer were standing about 10 meters off from the route side. equation 1 A noise degree associated at each edifice based on the traffic volume is calculated based on the shortest distance ( vitamin D ) between the noise beginning ( route ) and the edifice utilizing Euclidean geometry. The sound degree emanating from each route is obtained by rectifying the basic noise degree utilizing equation 2. The equation besides includes the tallness ( H ) of the hearer which is changeless in these computations. ( CRTN 1988 ) equation 2 To find the entire noise degree received by the edifice the corrected noise from each route must be summed over n roads in the development ( equation 3 ) equation 3 Each edifice will now hold a noise degree value stand foring the entire degree of noise associated with that edifices location in relation to the roads and their projected traffic flows. Our sustainability step is achieved by normalizing the noise degree ( 0-100 graduated table as before ) and using a non additive map ( equation 4 ( Highways Agency 1994 ) ) , this calculates the per centum of people that will be bothered by a specific degree of noise. equation 4Economic BenefitThe economic theoretical account utilises a discounted hard currency flow computation to find the worth of a edifices current hard currency flow for a specific point in clip. The computation uses a price reduction rate which allows the hard currency flows to be discounted back to their present worth. equation 5 Where CF = hard currency flow for that twelvemonth. R = price reduction rate for that twelvemonth. t = the twelvemonth. In the equation the capital cost for the building of the first edifice is represented by CF0. Capital costs of subsequent edifices will be discounted to this point clip. e.g. the capital cost of a edifice built two old ages after the initial edifice would be discounted utilizing. Each edifice in the simulation has a site readying and building stage, during this clip the hard currency flow in for that period is taken every bit 0 as the edifice would non yet be sold or rented. The simulation is able to reflect the differences between hard currency flows for rented and sold edifices. Buildings which are sold will take a big income at the point of sale. As the edifice has been sold farther hard currency flows for this edifice will be 0. The price reduction factor will besides use to the sale income so for two edifices of tantamount value, a edifice sold in twelvemonth one will hold a higher present value than constructing sold in twelvemonth 10. As the edifice has been sold the upkeep and care of the edifice will be borne by the purchaser and so it non modelled here. Buildings which are rented will take a smaller income every twelvemonth. Rented edifices may hold a rent free period, to promote renters, and will hold a laic period between rentals, during these tim es the hard currency flow for that period will be 0. A price reduction factor is applied to the annual income to find its present value, once more based on the building twelvemonth of the first building.. Fig 3: PV for a individual edifice, built in twelvemonth 0, demoing differences between leased and sold income with different price reduction rates. The initial cost of the edifices are calculated utilizing the edifice type ( e.g. residential, commercial, retail, societal ) and the cost per square meter for that type of edifice. The income from sale or rent is similarly calculated utilizing the jutting income for that type of edifice. These values were sourced from the SET economic study on the waterfront development ( Buchanan 2006 ) . The maximal and minimal valleies are so mapped onto 0 100 and linearly interpolated.CredenceAcceptance corresponds to the credence of possible edifice utilizations within the development. The masterplan for Dundee has been developed and it was possible through treatment with Dundee council to find the possible edifice utilizations which are under reappraisal and included commercial office infinite, retail units, cafe/bar/restaurant and residential infinite. The edifice usage study used a superior system where the participant was asked to rank possible edifice utilizations in order of penchant. If the participant had no penchant between the edifice uses at each rank the proportions chosen at each rank would be equal. To find if this is the instance Friedman trial was performed utilizing SPSS on the average rank of each edifice usage, with the void hypothesis being that the average ranks will be equal. Ranks Mean Rank Commercial 3.37 Retail 2.51 Leisure 1.54 Residential 2.58 Test Statistics a Sample Size 106 Chi-Square 107.264 df 3 Significance. .000 a. Friedman Test The consequences of the Friedman trial show that there is a important difference ( p & lt ; 0.001 ) between how the users ranked the different edifice utilizations. Combined with post-hoc analysis of the consequences it is possible to pattern the acceptableness edifice uses in the undermentioned order ; Leisure ( highest ranked ) , Retail & A ; Residential ( equal ranked ) and Commercial ( Lowest Ranked ) . To make a sustainability index for the acceptableness of each edifice these rankings are mapped onto a 0-100 graduated table, with Leisure at 100 ( highest sustainability ) , Retail & A ; Residential at 50 and Commercial ( lowest sustainability ) at 0.MULTICRITERIA OPINION ANALYSISOne of the jobs with traditional sustainability appraisal is affecting the positions and experiences of a broad scope of stakeholders ( ( Isaacs et al. 2010b ) , . Many of the traditional methods of aggregating index values, such as Multi Attribute Utility Theory ( MAUT ) , lack transparence go forthing the users in a place where they do non to the full understand how the resulting weightings have been derived ( Dodgson et al. 2009 ; Paracchini et Al. 2008 ) . The Analytic Network Process ( ANP ) method uses synergistic web constructions which give a more holistic representation of the overall job ( Saaty 2006 ) . Components of the job are connected, as appropriate, in braces with directed lines imitating the influence of one constituent over another. The constituents in a web may besides be regarded as elements that interact and influence each other in respect to a specific property. ( Saaty 2006 ) . To execute a ANP analysis the determination shaper must place the web through analysis of the job to be solved. The determination shaper must place the bunchs, elements and the relationships and interactions between them ( Bottero et al. 2007 ) . Once the determination shaper has constructed the web to be analysed they must now make a supermatrix depicting the interactions defined in the theoretical account ( Gencer and Gurpinar 2007 ) . The supermatrix is created utilizing the cardinal graduated table and pair-wise method every interaction is described in footings of every component it interacts with ( Saaty 1999 ) . Once this has been completed the normalised eigenvector calculated from the matrix will give the determination shaper the normalised prioritised list of elements. ANP allows cross-cluster interactions every bit good as inter-relationships between elements.. It is structured of course and allows for a more realistic representation of the job, but its chief strength lies in supplying the user with the ability to include their ain personal cognition and sentiments about an interaction through the usage of pair-wise comparings ( Saaty 2006, ; Bottero et Al. 2007 ) . The prioritised list of elements which are derived from the ANP analysis are used in the 3D visual image to supply the user with a individual of sustainability index if required. Al-Kodmany, K. ( 2002 ) Visual image tools and methods in community planning: from freehand studies to practical world. Journal of be aftering Literature, 17 ( 2 ) , p. 189. 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